Triple Quad 7500 Plus System (2024)

Overview

Have the confidence to tackle even the most challenging studies and run continuously at the highest level of performance

When you are under pressure to make critical decisions, you need a system innovated to rise to the challenge. Whether you're progressing high potency drug candidates into clinical trials, staying prepared for changing PFAS regulations, or investing years in researching a biomarker that could later be used by someone to help develop a diagnostic cancer test in a diagnostic application, the decisions you make count.

The next era of quantitation

The SCIEX 7500+ system takes precision quantitation to the next level. Achieve accurate results over sustained periods of time, across thousands of sample sets in increasingly complex matrices.Studies can be delivered in shorter timelines with the confidence to tackle new and emerging challenges.

Maintain our highest levels of sensitivity for up to twice as long in complex matrices, and develop resilient assays for even the most complex matrices.Increase the scope for large MRM panels with our fastest triple quad ever and take control of your instrument downtime with front-end user serviceability.

Mass Guard technology

This innovative technology reduces the risk andfrequency of instrument contamination by novel ion filtering prior to mass separation.​

Newly designed removableDJet+ assembly

The removable DJet+ assembly allows users to clean and maintain it themselves, making it easier to schedule front-end cleaning.

Speeds of up to 800 MRM per second

The fastest SCIEX triple quad yet increasing the scope for large quantitation panels that incorporate new compounds of concern.

High sensitivity, speed and resilience across large, complex sample sets

Delivering groundbreaking technology in the field of targeted quantitation, the SCIEX 7500+ system enables ultrasensitive levels of quantitation across drug development, emerging contaminants and life science research.The performance of the 7500+ system has been rigorously tested with accelerated high throughput assays on matrices notorious for causing instrument contamination. The system delivers sensitive, robust quantitation allowing you to quantify ultra low-levelcompounds in complex matrices with reduced risk of downtime.

Innovation in resilience delivers increased efficiency and reduced downtime.

Data

Experience both performance and reliability without compromise

  • Run for up to twice as long with no compromise in performance
  • Quantify more trace analytes at lower levels in complex matrices
  • Maximize your time and investment
  • Mass Guard technology filters ions prior to mass separation
  • Quickly develop methods for a wide variety of complex matrices
  • Benefit from the potential for reduced sample preparation
  • Our fastest SCIEX Triple Quad system yet enabled by new innovations in ion optics
  • Increase the scope for larger quantitation panels
  • Minimal need for method development
  • Easy monitoring and performance tracking means you can focus your attention where needed
  • Save time and reduce the potential for failed batches and repeat measurements
  • Triple Quad 7500 Plus System (1)
  • Triple Quad 7500 Plus System (2)
  • Triple Quad 7500 Plus System (3)

Figure 1. Peak area ratio (raw peak area normalized to IS) from analysis of alprazolam, a pharmaceutical small molecule, and sulfamethoxazole SST (A) and rat plasma matrix (B) injections on the SCIEX 7500+ system. Internal standard-corrected data for 3 drug compounds, showing %CVs of 3-5% across more than 10,000 injections of rat plasma.

Figure 2. Representative XICs of an example herbicide, diuron, in the solvent blank, in solvent standards at the LLOQ of 10 ng/L and 100 ng/L and in orange juice post-spiked at 100 ng/L acquired in positive polarity using the SCIEX 7500+ system.

Figure 3. Raw peak areas normalized to initial response (A) and internal standard (IS)-corrected peak area ratios (B) for perfluorooctane sulfonate (PFOS) in solvent quality control (QC) samples on the SCIEX 7500 (blue) and on the SCIEX 7500+ (green) systems. Stability of quantitation for PFOS across ~7000 injections of a variety of complex matrices. 11 of 13 PFAS compounds showed up to a 2x improvement in the number of injections performance could be maintained over versus the 7500.

    Promise more from your investment

    • Triple Quad 7500 Plus System (4)

      Maximize your investment with the SCIEX LC-MS Protect Plus Plan

      A comprehensive coverage plan that ensures uptime, increases productivity, and generates more throughput. Take advantage of customer-serviceable technology and owner discounts for self-serviceable maintenance and enjoy on-site response, full coverage for parts, labor, and travel, planned maintenance visits, and telephone support.

      To access further savings on software licenses and validation services, seamlessly transfer from your warranty period to a service package for uninterrupted lab operations.

      *Please note that the SCIEX LC-MS Protect Plus Plan is exclusively available at the time of instrument purchase.

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      LC-MS service and support plans designed to provide the confidence you need to achieve your analytical goals.

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      Keep your results on the cutting edge with a support plan for your operating and processing software. Use your SCIEX software with confidence that it is up to date and secure.

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      StatusScope remote monitoring service

      Experience real-time diagnosis, monitoring, and resolution of your system, and get full visibility into critical parameters directly in your SCIEX Now dashboard.

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      SCIEX Now Visual Assist augmented reality remote support

      Bring your system back online in minutes instead of hours. Receive immediate visual support from a SCIEX service engineer while in front of your instrument.

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      SCIEX Now Learning Hub Success Programs

      Get the training your team needs to succeed with SCIEX Now Learning Hub Success Programs.

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      Triple Quad 7500 Plus System (2024)
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